human ABCB4 Adenovirus

Name
Ad-h-ABCB4

Cat No
ADV-200058

Availability
4-5 weeks

This is an Adenovirus expressing Human ABCB4.

ADV-200058

Ad-h-ABCB4

Ready-to-use Adenovirus expressing Human ABCB4 (ATP binding cassette subfamily B member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ABC21; GBD1; ICP3; MDR2; MDR2/3; MDR3; PFIC-3; PGY3

Description (Vector)

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.

Gene ID

5244

Gene Name (Vector)

ATP binding cassette subfamily B member 4

Gene Symbol

ABCB4

HGNC ID

HGNC:45

ORF Size (aa)

3861

ORF Size (bp)

3861 bp

RefSeq ID

NM_000443

RefSeq Synonyms

NM_018850, NM_018849, NM_000443, BC042531,

Species

human

UniGene ID

Hs.654403

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.