rat ING4 Over-expression AAV
This is an AAV expressing Rat Ing4.
AAV-295107
AAV-r-ING4
Ready-to-use AAV expressing Rat Ing4 (inhibitor of growth family, member 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1).
Gene ID
297597
Gene Name (Vector)
inhibitor of growth family, member 4
Gene Symbol
Ing4
ORF Size (aa)
738
ORF Size (bp)
738 bp
RefSeq ID
NM_001079887
RefSeq Synonyms
NM_001079887, BC127511,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.