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rat RGD1306772 Over-expression AAV

Name 
AAV-r-RGD1306772
Cat No 
AAV-294751
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Rat Rita1.

AAV-294751
AAV-r-RGD1306772

Ready-to-use AAV expressing Rat Rita1 (RBPJ interacting and tubulin associated 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
RGD1306772; Rita
Description (Vector)
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.
Gene ID
288683
Gene Name (Vector)
RBPJ interacting and tubulin associated 1
Gene Symbol
Rita1
ORF Size (aa)
777
RefSeq ID
NM_001044226
RefSeq Synonyms
NM_001044226, BC112384,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.