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rat NPAP60 Over-expression AAV

Name 
AAV-r-NPAP60
Cat No 
AAV-294609
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Rat Nup50.

AAV-294609
AAV-r-NPAP60

Ready-to-use AAV expressing Rat Nup50 (nucleoporin 50). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Npap60; Rtp60
Description (Vector)
Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with multiple transport receptor proteins including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.
Gene ID
25497
Gene Name (Vector)
nucleoporin 50
Gene Symbol
Nup50
ORF Size (aa)
1404
ORF Size (bp)
1404 bp
RefSeq ID
NM_012991
RefSeq Synonyms
NM_012991, BC097337, BC079001,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.