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rat NR1H4 Over-expression AAV

Name 
AAV-r-NR1H4
Cat No 
AAV-293596
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Rat Nr1h4.

AAV-293596
AAV-r-NR1H4

Ready-to-use AAV expressing Rat Nr1h4 (nuclear receptor subfamily 1, group H, member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Fxr
Description (Vector)
Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.
Gene ID
60351
Gene Name (Vector)
nuclear receptor subfamily 1, group H, member 4
Gene Symbol
Nr1h4
ORF Size (aa)
1452
ORF Size (bp)
1452 bp
RefSeq ID
NM_021745
RefSeq Synonyms
NM_021745, BC083815,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.