rat SIKE Over-expression AAV
This is an AAV expressing Rat Sike1.
AAV-293242
AAV-r-SIKE
Ready-to-use AAV expressing Rat Sike1 (suppressor of IKBKE 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RGD1311316; Sike
Description (Vector)
Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways.
Gene ID
362007
Gene Name (Vector)
suppressor of IKBKE 1
Gene Symbol
Sike1
ORF Size (aa)
624
RefSeq ID
NM_001012182
RefSeq Synonyms
NM_001012182, BC089208,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.