rat ALKBH3 Over-expression AAV
This is an AAV expressing Rat Alkbh3.
AAV-291866
AAV-r-ALKBH3
Ready-to-use AAV expressing Rat Alkbh3 (alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.
Gene ID
362169
Gene Name (Vector)
alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase
Gene Symbol
Alkbh3
ORF Size (aa)
888
ORF Size (bp)
888 bp
RefSeq ID
NM_001014180
RefSeq Synonyms
NM_001014180, BC083756,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.