rat ITM2B Over-expression AAV

Name 
AAV-r-ITM2B
Cat No 
AAV-291389
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Rat Itm2b.

AAV-291389
AAV-r-ITM2B

Ready-to-use AAV expressing Rat Itm2b (integral membrane protein 2B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Bri; imBRI2
Description (Vector)
Plays a regulatory role in the processing of the beta-amyloid A4 precursor protein (APP) and acts as an inhibitor of the beta-amyloid peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites|Function: Mature BRI2 (mBRI2) functions as a modulator of the beta-amyloid A4 precursor protein (APP) processing leading to a strong reduction in the secretion of secretase-processed beta-amyloid protein 40 and beta-amyloid protein 42|Function: Bri23 peptide prevents aggregation of APP beta-amyloid protein 42 peptide into toxic oligomers.
Gene ID
290364
Gene Name (Vector)
integral membrane protein 2B
Gene Symbol
Itm2b
ORF Size (aa)
801
RefSeq ID
NM_001006963
RefSeq Synonyms
NM_001006963, BC083735,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.