rat PTBP2 Over-expression AAV

Name
AAV-r-PTBP2

Cat No
AAV-290925

Availability
4-5 weeks

This is an AAV expressing Rat Ptbp2.

AAV-290925

AAV-r-PTBP2

Ready-to-use AAV expressing Rat Ptbp2 (polypyrimidine tract binding protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Ptb2; PTBLP; PTBLP-L; PTBLP-S

Description (Vector)

RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. Beside its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.

Gene ID

310820

Gene Name (Vector)

polypyrimidine tract binding protein 2

Gene Symbol

Ptbp2

ORF Size (aa)

1596

ORF Size (bp)

1596 bp

RefSeq ID

NM_001005555

RefSeq Synonyms

NM_001005555, BC082076,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.