rat MAP3K11 Over-expression AAV

Name
AAV-r-MAP3K11

Cat No
AAV-290751

Availability
4-5 weeks

This is an AAV expressing Rat Map3k11.

AAV-290751

AAV-r-MAP3K11

Ready-to-use AAV expressing Rat Map3k11 (mitogen-activated protein kinase kinase kinase 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Mlk-3; Mlk3; RHOE

Description (Vector)

Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.

Gene ID

309168

Gene Name (Vector)

mitogen-activated protein kinase kinase kinase 11

Gene Symbol

Map3k11

ORF Size (aa)

2553

ORF Size (bp)

2553 bp

RefSeq ID

NM_001013150

RefSeq Synonyms

NM_001013150, BC081952,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.