rat GM2A Over-expression AAV
This is an AAV expressing Rat Gm2a.
AAV-290666
AAV-r-GM2A
Ready-to-use AAV expressing Rat Gm2a (GM2 ganglioside activator). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
Gene ID
282838
Gene Name (Vector)
GM2 ganglioside activator
Gene Symbol
Gm2a
ORF Size (aa)
600
RefSeq ID
NM_172335
RefSeq Synonyms
NM_172335, BC072474,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.