rat TSC22D3 Over-expression AAV
This is an AAV expressing Rat Tsc22d3.
AAV-290539
AAV-r-TSC22D3
Ready-to-use AAV expressing Rat Tsc22d3 (TSC22 domain family, member 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Dsipi; Gilz
Description (Vector)
Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities (By similarity).
Gene ID
83514
Gene Name (Vector)
TSC22 domain family, member 3
Gene Symbol
Tsc22d3
ORF Size (aa)
405
RefSeq ID
NM_031345
RefSeq Synonyms
NM_031345, BC061979,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.