rat RAN Over-expression AAV

Name
AAV-r-RAN

Cat No
AAV-290057

Availability
4-5 weeks

This is an AAV expressing Rat Ran.

AAV-290057

AAV-r-RAN

Ready-to-use AAV expressing Rat Ran (RAN, member RAS oncogene family). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2|Function: Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.

Gene ID

84509

Gene Name (Vector)

RAN, member RAS oncogene family

Gene Symbol

Ran

ORF Size (aa)

651

ORF Size (bp)

651 bp

RefSeq ID

NM_053439

RefSeq Synonyms

NM_053439, BC059123,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.