mouse TLR3 Over-expression AAV
This is an AAV expressing Mouse Tlr3.
AAV-281163
AAV-m-TLR3
Ready-to-use AAV expressing Mouse Tlr3 (toll-like receptor 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI957183
Description (Vector)
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Gene ID
142980
Gene Name (Vector)
toll-like receptor 3
Gene Symbol
Tlr3
ORF Size (aa)
2718
ORF Size (bp)
2718 bp
RefSeq ID
NM_126166
RefSeq Synonyms
NM_126166, BC099937,
Species
mouse
UniGene ID
Mm.33874
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.