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mouse RNF139 Over-expression AAV

Name 
AAV-m-RNF139
Cat No 
AAV-281056
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Rnf139.

AAV-281056
AAV-m-RNF139

Ready-to-use AAV expressing Mouse Rnf139 (ring finger protein 139). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
4930555P18Rik
Description (Vector)
E3-ubiquitin ligase; acts as a negative regulator of the cell proliferation through mechanisms involving G2/M arrest and cell death. Required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER). Affects SREBP processing by hindering the SREBP/SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression. Required for INSIG1 ubiquitination. May be required for EIF3 complex ubiquitination. May function as a signaling receptor.
Gene ID
75841
Gene Name (Vector)
ring finger protein 139
Gene Symbol
Rnf139
ORF Size (aa)
2007
ORF Size (bp)
2007 bp
RefSeq ID
NM_175226
RefSeq Synonyms
NM_175226, BC052901,
Species
mouse
UniGene ID
Mm.460627

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.