mouse PNPLA2 Over-expression AAV

Name
AAV-m-PNPLA2

Cat No
AAV-280982

Availability
4-5 weeks

This is an AAV expressing Mouse Pnpla2.

AAV-280982

AAV-m-PNPLA2

Ready-to-use AAV expressing Mouse Pnpla2 (patatin-like phospholipase domain containing 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

0610039C21Rik; 1110001C14Rik; Atgl; TTS-2.2

Description (Vector)

Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.

Gene ID

66853

Gene Name (Vector)

patatin-like phospholipase domain containing 2

Gene Symbol

Pnpla2

ORF Size (aa)

1461

ORF Size (bp)

1461 bp

RefSeq ID

NM_025802

RefSeq Synonyms

NM_025802, NM_001163689, BC064747, BC044781, BC019188,

Species

mouse

UniGene ID

Mm.29998

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.