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mouse EYA1 Over-expression AAV

Name 
AAV-m-EYA1
Cat No 
AAV-280731
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Eya1.

AAV-280731
AAV-m-EYA1

Ready-to-use AAV expressing Mouse Eya1 (EYA transcriptional coactivator and phosphatase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bor
Description (Vector)
Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. Seems to coactivate SIX2, SIX4 and SIX5. May be required for normal development of branchial arches, ear and kidney.
Gene ID
14048
Gene Name (Vector)
EYA transcriptional coactivator and phosphatase 1
Gene Symbol
Eya1
ORF Size (aa)
1758
ORF Size (bp)
1758 bp
RefSeq ID
NM_010164
RefSeq Synonyms
NM_010164, NM_001310459, NM_001252192, BC066860, BC060260,
Species
mouse
UniGene ID
Mm.250185

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.