mouse ZIC2 Over-expression AAV

Name 
AAV-m-ZIC2
Cat No 
AAV-277065
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Zic2.

AAV-277065
AAV-m-ZIC2

Ready-to-use AAV expressing Mouse Zic2 (zinc finger protein of the cerebellum 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HPE5; Ku
Description (Vector)
Acts as a transcriptional activator or repressor. Plays important roles in the early stage of organogenesis of the CNS. Activates the transcription of the serotonin transporter SERT in uncrossed ipsilateral retinal ganglion cells (iRGCs) to refine eye-specific projections in primary visual targets. Its transcriptional activity is repressed by MDFIC. Involved in the formation of the ipsilateral retinal projection at the optic chiasm midline. Drives the expression of EPHB1 on ipsilaterally projecting growth cones. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'. Associates to the basal SERT promoter region from ventrotemporal retinal segments of retinal embryos.
Gene ID
22772
Gene Name (Vector)
zinc finger protein of the cerebellum 2
Gene Symbol
Zic2
ORF Size (aa)
1587
ORF Size (bp)
1587 bp
RefSeq ID
NM_009574
RefSeq Synonyms
NM_009574, BC156493,
Species
mouse
UniGene ID
Mm.308936

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.