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mouse ZEB1 Over-expression AAV

Name 
AAV-m-ZEB1
Cat No 
AAV-276639
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Zeb1.

AAV-276639
AAV-m-ZEB1

Ready-to-use AAV expressing Mouse Zeb1 (zinc finger E-box binding homeobox 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
3110032K11Rik; AREB6; BZP; MEB1; Nil2; TCF-8; Tcf18; Tcf8; Tw; ZEB; Zfhep; Zfhx1a; Zfx1a; Zfx1ha; [delta]EF1
Description (Vector)
Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
Gene ID
21417
Gene Name (Vector)
zinc finger E-box binding homeobox 1
Gene Symbol
Zeb1
ORF Size (aa)
3354
ORF Size (bp)
3354 bp
RefSeq ID
NM_011546
RefSeq Synonyms
NM_011546, BC139769, BC139768,
Species
mouse
UniGene ID
Mm.3929

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.