mouse TIMP2 Over-expression AAV

Name
AAV-m-TIMP2

Cat No
AAV-274232

Availability
4-5 weeks

This is an AAV expressing Mouse Timp2.

AAV-274232

AAV-m-TIMP2

Ready-to-use AAV expressing Mouse Timp2 (tissue inhibitor of metalloproteinase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

D11Bwg1104e; Timp-2

Description (Vector)

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.

Gene ID

21858

Gene Name (Vector)

tissue inhibitor of metalloproteinase 2

Gene Symbol

Timp2

ORF Size (aa)

663

ORF Size (bp)

663 bp

RefSeq ID

NM_011594

RefSeq Synonyms

NM_011594, BC049126,

Species

mouse

UniGene ID

Mm.206505

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.