mouse SREBF1 Over-expression AAV

Name 
AAV-m-SREBF1
Cat No 
AAV-273127
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Srebf1.

AAV-273127
AAV-m-SREBF1

Ready-to-use AAV expressing Mouse Srebf1 (sterol regulatory element binding transcription factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ADD1; bHLHd1; SREBP-1a; SREBP1; SREBP1c
Description (Vector)
Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway (By similarity). Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3').
Gene ID
20787
Gene Name (Vector)
sterol regulatory element binding transcription factor 1
Gene Symbol
Srebf1
ORF Size (aa)
3405
ORF Size (bp)
3405 bp
RefSeq ID
NM_011480
RefSeq Synonyms
NM_011480, NM_001313979, BC056922,
Species
mouse
UniGene ID
Mm.278701

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.