mouse SMO Over-expression AAV

Name 
AAV-m-SMO
Cat No 
AAV-272651
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Smo.

AAV-272651
AAV-m-SMO

Ready-to-use AAV expressing Mouse Smo (smoothened, frizzled class receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bnb; E130215L21Rik; Smoh; smoothened
Description (Vector)
G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
Gene ID
319757
Gene Name (Vector)
smoothened, frizzled class receptor
Gene Symbol
Smo
ORF Size (aa)
1320
ORF Size (bp)
1320 bp
RefSeq ID
NM_176996
RefSeq Synonyms
NM_176996, BC096028, BC048091,
Species
mouse
UniGene ID
Mm.29279

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.