mouse SELP Over-expression AAV

Name 
AAV-m-SELP
Cat No 
AAV-271577
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Selp.

AAV-271577
AAV-m-SELP

Ready-to-use AAV expressing Mouse Selp (selectin, platelet). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD antigen CD62P;CD62 antigen-like family member P;CD62P;GMP-140;granule membrane protein 140;Grmp;LECAM3;leukocyte-endothelial cell adhesion molecule 3;PADGEM;platelet activation dependent granule-external membrane protein;P-selectin
Description (eCommerce)
P-Selectin, or CD62P, is a Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. It mediates the interaction of activated endothelial cells or platelets with leukocytes. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P16109].
Description (Vector)
Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1.
Gene ID
20344
Gene Name (eCommerce)
selectin, platelet
Gene Name (Vector)
selectin, platelet
Gene Symbol
Selp
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
2307
ORF Size (bp)
2307 bp
Protein Name (eCommerce)
P-selectin
RefSeq ID
NM_011347
RefSeq Synonyms
NM_011347, BC109159, BC109158,
Research Areas (Faceted)
immunology,cardiovascular
Species
mouse
Target Sentence
P-Selectin, or CD62P, is a Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. It mediates the interaction of activated endothelial cells or platelets with leukocytes. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P16109].
UniGene ID
Mm.3337
UniProt ID (eCommerce)
Q01102

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.