mouse RFX6 Over-expression AAV

Name 
AAV-m-RFX6
Cat No 
AAV-270452
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Rfx6.

AAV-270452
AAV-m-RFX6

Ready-to-use AAV expressing Mouse Rfx6 (regulatory factor X, 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
4930572O07Rik; Rfxdc1
Description (Vector)
Transcription factor required to direct islet cell differentiation during endocrine pancreas development. Specifically required for the differentiation of 4 of the 5 islet cell types and for the production of insulin. Not required for pancreatic PP (polypeptide-producing) cells differentiation. Acts downstream of NEUROG3 and regulates the transcription factors involved in beta-cell maturation and function, thereby restricting the expression of the beta-cell differentiation and specification genes, and thus the beta-cell fate choice. Activates transcription by forming a heterodimer with RFX3 and binding to the X-box in the promoter of target genes.
Gene ID
320995
Gene Name (Vector)
regulatory factor X, 6
Gene Symbol
Rfx6
ORF Size (aa)
1992
ORF Size (bp)
1992 bp
RefSeq ID
NM_177306
RefSeq Synonyms
NM_177306, NM_001159389, BC132294, BC132104,
Species
mouse
UniGene ID
Mm.109190

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.