mouse PEO1 Over-expression AAV

Name 
AAV-m-PEO1
Cat No 
AAV-268396
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Twnk.

AAV-268396
AAV-m-PEO1

Ready-to-use AAV expressing Mouse Twnk (twinkle mtDNA helicase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
D19Ertd626e; PEO; Peo1; Twinl
Description (Vector)
Involved in mitochondrial DNA (mtDNA) metabolism. Could function as an adenine nucleotide-dependent DNA helicase. Function inferred to be critical for lifetime maintenance of mtDNA integrity. In vitro, forms in combination with POLG, a processive replication machinery, which can use double-stranded DNA (dsDNA) as template to synthesize single-stranded DNA (ssDNA) molecules. May be a key regulator of mtDNA copy number in mammals (By similarity).
Gene ID
226153
Gene Name (Vector)
twinkle mtDNA helicase
Gene Symbol
Twnk
ORF Size (aa)
2058
ORF Size (bp)
2058 bp
RefSeq ID
NM_153796
RefSeq Synonyms
NM_153796, BC071195,
Species
mouse
UniGene ID
Mm.105585

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.