mouse PAM Over-expression AAV

Name
AAV-m-PAM

Cat No
AAV-268027

Availability
4-5 weeks

This is an AAV expressing Mouse Pam.

AAV-268027

AAV-m-PAM

Ready-to-use AAV expressing Mouse Pam (peptidylglycine alpha-amidating monooxygenase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PHM

Description (Vector)

Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity.

Gene ID

18484

Gene Name (Vector)

peptidylglycine alpha-amidating monooxygenase

Gene Symbol

Pam

ORF Size (aa)

2937

ORF Size (bp)

2937 bp

RefSeq ID

NM_013626

RefSeq Synonyms

NM_013626, BC166013,

Species

mouse

UniGene ID

Mm.441453

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.