mouse NUDT15 Over-expression AAV

Name
AAV-m-NUDT15

Cat No
AAV-266181

Availability
4-5 weeks

This is an AAV expressing Mouse Nudt15.

AAV-266181

AAV-m-NUDT15

Ready-to-use AAV expressing Mouse Nudt15 (nudix (nucleoside diphosphate linked moiety X)-type motif 15). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

6530403O17; A730068G11Rik; MTH2

Description (Vector)

Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear (By similarity). May have a role in DNA synthesis and cell cycle progression through the interaction with PCNA.

Gene ID

214254

Gene Name (Vector)

nudix (nucleoside diphosphate linked moiety X)-type motif 15

Gene Symbol

Nudt15

ORF Size (aa)

513

RefSeq ID

NM_172527

RefSeq Synonyms

NM_172527, BC060962,

Species

mouse

UniGene ID

Mm.386852

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.