mouse NKX2-2 Over-expression AAV

Name 
AAV-m-NKX2-2
Cat No 
AAV-265814
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Nkx2-2.

AAV-265814
AAV-m-NKX2-2

Ready-to-use AAV expressing Mouse Nkx2-2 (NK2 homeobox 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Nkx-2.2; Nkx2.2; tinman
Description (Vector)
Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity).
Gene ID
18088
Gene Name (Vector)
NK2 homeobox 2
Gene Symbol
Nkx2-2
ORF Size (aa)
822
ORF Size (bp)
822 bp
RefSeq ID
NM_010919
RefSeq Synonyms
NM_010919, NM_001077632, BC138160, BC138159,
Species
mouse
UniGene ID
Mm.330639

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.