mouse NEURL2 Over-expression AAV

Name
AAV-m-NEURL2

Cat No
AAV-265684

Availability
4-5 weeks

This is an AAV expressing Mouse Neurl2.

AAV-265684

AAV-m-NEURL2

Ready-to-use AAV expressing Mouse Neurl2 (neuralized E3 ubiquitin protein ligase 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Neur2; Ozz; Ozz-E3

Description (Vector)

Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By similarity).

Gene ID

415115

Gene Name (Vector)

neuralized E3 ubiquitin protein ligase 2

Gene Symbol

Neurl2

ORF Size (aa)

858

RefSeq ID

NM_001082974

RefSeq Synonyms

NM_001082974, BC156597, BC148675,

Species

mouse

UniGene ID

Mm.474586

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.