mouse MUL1 Over-expression AAV

Name 
AAV-m-MUL1
Cat No 
AAV-265196
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Mul1.

AAV-265196
AAV-m-MUL1

Ready-to-use AAV expressing Mouse Mul1 (mitochondrial ubiquitin ligase activator of NFKB 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
0610009K11Rik; AV000801; Gide
Description (Vector)
Exhibits weak E3 ubiquitin-protein ligase activity, but preferentially acts as a SUMO E3 ligase at physiological concentrations. Plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Gene ID
68350
Gene Name (Vector)
mitochondrial ubiquitin ligase activator of NFKB 1
Gene Symbol
Mul1
ORF Size (aa)
1059
ORF Size (bp)
1059 bp
RefSeq ID
NM_026689
RefSeq Synonyms
NM_026689, BC019516,
Species
mouse
UniGene ID
Mm.103413

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.