mouse MPRIP Over-expression AAV

Name 
AAV-m-MPRIP
Cat No 
AAV-264852
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Mprip.

AAV-264852
AAV-m-MPRIP

Ready-to-use AAV expressing Mouse Mprip (myosin phosphatase Rho interacting protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
9530046C02; AA536749; AI647711; C76423; mKIAA0864; p116Rip; Rhoip3; RIP3
Description (Vector)
Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
Gene ID
26936
Gene Name (Vector)
myosin phosphatase Rho interacting protein
Gene Symbol
Mprip
ORF Size (aa)
3114
ORF Size (bp)
3114 bp
RefSeq ID
NM_201245
RefSeq Synonyms
NM_201245, NM_012027, BC063067,
Species
mouse
UniGene ID
Mm.392074

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.