mouse MLF1 Over-expression AAV

Name
AAV-m-MLF1

Cat No
AAV-264686

Availability
4-5 weeks

This is an AAV expressing Mouse Mlf1.

AAV-264686

AAV-m-MLF1

Ready-to-use AAV expressing Mouse Mlf1 (myeloid leukemia factor 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HLS7

Description (Vector)

Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Gene ID

17349

Gene Name (Vector)

myeloid leukemia factor 1

Gene Symbol

Mlf1

ORF Size (aa)

849

ORF Size (bp)

849 bp

RefSeq ID

NM_010801

RefSeq Synonyms

NM_010801, NM_001039543, BC027526,

Species

mouse

UniGene ID

Mm.10414

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.