mouse MCF2 Over-expression AAV

Name 
AAV-m-MCF2
Cat No 
AAV-264361
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Mcf2.

AAV-264361
AAV-m-MCF2

Ready-to-use AAV expressing Mouse Mcf2 (mcf.2 transforming sequence). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
B230117G22Rik; Dbl; Mcf-2
Description (Vector)
Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42. Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42.
Gene ID
109904
Gene Name (Vector)
mcf.2 transforming sequence
Gene Symbol
Mcf2
ORF Size (aa)
2787
ORF Size (bp)
2787 bp
RefSeq ID
NM_133197
RefSeq Synonyms
NM_133197, NM_001289731, NM_001289730, BC125435,
Species
mouse
UniGene ID
Mm.93796

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.