mouse MAEL Over-expression AAV

Name 
AAV-m-MAEL
Cat No 
AAV-264079
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Mael.

AAV-264079
AAV-m-MAEL

Ready-to-use AAV expressing Mouse Mael (maelstrom spermatogenic transposon silencer). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
4933405K18Rik; AU019877
Description (Vector)
Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for localization of germ-cell factors to the meiotic nuage (By similarity).
Gene ID
98558
Gene Name (Vector)
maelstrom spermatogenic transposon silencer
Gene Symbol
Mael
ORF Size (aa)
1305
ORF Size (bp)
1305 bp
RefSeq ID
NM_175296
RefSeq Synonyms
NM_175296, BC050800,
Species
mouse
UniGene ID
Mm.26189

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.