mouse LRWD1 Over-expression AAV

Name 
AAV-m-LRWD1
Cat No 
AAV-263918
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Lrwd1.

AAV-263918
AAV-m-LRWD1

Ready-to-use AAV expressing Mouse Lrwd1 (leucine-rich repeats and WD repeat domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1200011O22Rik; AU042569; AW548074; Orca
Description (Vector)
Associated component of the origin recognition complex (ORC) required to recruit and stabilize the ORC complex to chromatin. Probably required for the association of ORC on chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin: binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. It is unclear whether it recongnizes and binds these repressive marks by itself or needs additional factors.
Gene ID
71735
Gene Name (Vector)
leucine-rich repeats and WD repeat domain containing 1
Gene Symbol
Lrwd1
ORF Size (aa)
1947
ORF Size (bp)
1947 bp
RefSeq ID
NM_027891
RefSeq Synonyms
NM_027891, BC048397,
Species
mouse
UniGene ID
Mm.425292

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.