mouse LAG3 Over-expression AAV

Name 
AAV-m-LAG3
Cat No 
AAV-263224
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Lag3.

AAV-263224
AAV-m-LAG3

Ready-to-use AAV expressing Mouse Lag3 (lymphocyte-activation gene 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD antigen CD223;CD223;LAG-3;Ly66;lymphocyte activation gene 3 protein
Description (eCommerce)
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4 [taken from NCBI Entrez Gene (Gene ID: 3902)]
Description (Vector)
Involved in lymphocyte activation. Binds to HLA class-II antigens.
Gene ID
16768
Gene Name (eCommerce)
lymphocyte-activation gene 3
Gene Name (Vector)
lymphocyte-activation gene 3
Gene Symbol
Lag3
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
1566
ORF Size (bp)
1566 bp
Protein Name (eCommerce)
Lymphocyte activation gene 3 protein
RefSeq ID
NM_008479
RefSeq Synonyms
NM_008479, BC120591,
Research Areas
Immune cells & tumor markers,Immune-checkpoints,Immunology,Immuno-Oncology,Signal Transduction,T cell markers
Research Areas (Faceted)
immuno_oncology,immunology,signal_transduction
Species
mouse
Target Sentence
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4 [taken from NCBI Entrez Gene (Gene ID: 3902)]
UniGene ID
Mm.4528
UniProt ID (eCommerce)
Q61790

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.