mouse KDM2B Over-expression AAV

Name 
AAV-m-KDM2B
Cat No 
AAV-262760
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse KDM2B.

AAV-262760
AAV-m-KDM2B

Ready-to-use AAV expressing Mouse KDM2B (lysine (K)-specific demethylase 2B). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Cxxc2; Fbl10; Fbxl10; Jhdm1b; PCCX2
Description (Vector)
Histone demethylase that demethylates 'Lys-4' and 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' and dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Gene ID
30841
Gene Name (Vector)
lysine (K)-specific demethylase 2B
Gene Symbol
KDM2B
ORF Size (aa)
2331
ORF Size (bp)
2331 bp
RefSeq ID
NM_001003953
RefSeq Synonyms
NM_013910, NM_001005866, NM_001003953, BC065090, BC057622,
Species
mouse
UniGene ID
Mm.86406

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.