mouse ITM2C Over-expression AAV

Name 
AAV-m-ITM2C
Cat No 
AAV-262480
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Itm2c.

AAV-262480
AAV-m-ITM2C

Ready-to-use AAV expressing Mouse Itm2c (integral membrane protein 2C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
3110038L02Rik; BRI3; Bricd2c; E25; E25C; ITM3
Description (Vector)
Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).
Gene ID
64294
Gene Name (Vector)
integral membrane protein 2C
Gene Symbol
Itm2c
ORF Size (aa)
810
RefSeq ID
NM_022417
RefSeq Synonyms
NM_022417, BC012952,
Species
mouse
UniGene ID
Mm.29870

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.