mouse IRF8 Over-expression AAV

Name 
AAV-m-IRF8
Cat No 
AAV-262374
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Irf8.

AAV-262374
AAV-m-IRF8

Ready-to-use AAV expressing Mouse Irf8 (interferon regulatory factor 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI893568; ICSBP; Icsbp1; interferon consensus sequence binding protein 1; interferon consensus sequence-binding protein; interferon regulatory factor 8; IRF-8; Myls
Description (eCommerce)
Interferon regulatory factor (IRF8) is a member of the IRF family of transcription factors that plays a critical role in immune cell function and development. IRF8 has been shown to be an important regulator of CD8 T-cell differentiation.
Description (Vector)
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a negative regulatory role in cells of the immune system.
Gene ID
15900
Gene Name (eCommerce)
interferon regulatory factor 8
Gene Name (Vector)
interferon regulatory factor 8
Gene Symbol
Irf8
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
1275
ORF Size (bp)
1275 bp
Protein Name (eCommerce)
Interferon regulatory factor 8
RefSeq ID
NM_008320
RefSeq Synonyms
NM_008320, NM_001301811, BC005450,
Research Areas
Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
mouse
Target Sentence
Interferon regulatory factor (IRF8) is a member of the IRF family of transcription factors that plays a critical role in immune cell function and development. IRF8 has been shown to be an important regulator of CD8 T-cell differentiation.
UniGene ID
Mm.334861
UniProt ID (eCommerce)
P23611

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.