mouse IL1R1 Over-expression AAV

Name 
AAV-m-IL1R1
Cat No 
AAV-262138
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Il1r1.

AAV-262138
AAV-m-IL1R1

Ready-to-use AAV expressing Mouse Il1r1 (interleukin 1 receptor, type I). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD121a; CD121b; IL-1R1; IL-iR; Il1r-1
Description (Vector)
Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.
Gene ID
16177
Gene Name (Vector)
interleukin 1 receptor, type I
Gene Symbol
Il1r1
ORF Size (aa)
1731
ORF Size (bp)
1731 bp
RefSeq ID
NM_008362
RefSeq Synonyms
NM_008362, NM_001123382, BC109135,
Species
mouse
UniGene ID
Mm.896

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.