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mouse GRPEL2 Over-expression AAV

Name 
AAV-m-GRPEL2
Cat No 
AAV-260803
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Grpel2.

AAV-260803
AAV-m-GRPEL2

Ready-to-use AAV expressing Mouse Grpel2 (GrpE-like 2, mitochondrial). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
mt-GrpE#2; mt-Grpel2
Description (Vector)
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70 (By similarity).
Gene ID
17714
Gene Name (Vector)
GrpE-like 2, mitochondrial
Gene Symbol
Grpel2
ORF Size (aa)
675
ORF Size (bp)
675 bp
RefSeq ID
NM_021296
RefSeq Synonyms
NM_021296, BC120747, BC068232,
Species
mouse
UniGene ID
Mm.269657

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.