mouse GRK4 Over-expression AAV

Name 
AAV-m-GRK4
Cat No 
AAV-260781
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Grk4.

AAV-260781
AAV-m-GRK4

Ready-to-use AAV expressing Mouse Grk4 (G protein-coupled receptor kinase 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A830025H08Rik; Gprk2l; Gprk4; GRK
Description (Vector)
Specifically phosphorylates the activated forms of G protein-coupled receptors. GRK4-alpha can phosphorylate rhodopsin and its activity is inhibited by calmodulin; the other three isoforms do not phosphorylate rhodopsin and do not interact with calmodulin. GRK4-alpha and GRK4-gamma phosphorylate DRD3. Phosphorylates ADRB2.
Gene ID
14772
Gene Name (Vector)
G protein-coupled receptor kinase 4
Gene Symbol
Grk4
ORF Size (aa)
1725
ORF Size (bp)
1725 bp
RefSeq ID
NM_019497
RefSeq Synonyms
NM_019497, NM_001080743, BC150691,
Species
mouse
UniGene ID
Mm.117076

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.