mouse GPBAR1 Over-expression AAV

Name
AAV-m-GPBAR1

Cat No
AAV-260493

Availability
4-5 weeks

This is an AAV expressing Mouse Gpbar1.

AAV-260493

AAV-m-GPBAR1

Ready-to-use AAV expressing Mouse Gpbar1 (G protein-coupled bile acid receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BG37; GPCR; GPR131; M-BAR; TGR5

Description (Vector)

Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids.

Gene ID

227289

Gene Name (Vector)

G protein-coupled bile acid receptor 1

Gene Symbol

Gpbar1

ORF Size (aa)

990

RefSeq ID

NM_174985

RefSeq Synonyms

NM_174985, BC119327, BC116914,

Species

mouse

UniGene ID

Mm.246587

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.