mouse FNBP1L Over-expression AAV

Name 
AAV-m-FNBP1L
Cat No 
AAV-259521
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Fnbp1l.

AAV-259521
AAV-m-FNBP1L

Ready-to-use AAV expressing Mouse Fnbp1l (formin binding protein 1-like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2610318I01Rik; AW548221; toca-1; TOCA1
Description (Vector)
Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular bacterial pathogens.
Gene ID
214459
Gene Name (Vector)
formin binding protein 1-like
Gene Symbol
Fnbp1l
ORF Size (aa)
1116
ORF Size (bp)
1116 bp
RefSeq ID
NM_153118
RefSeq Synonyms
NM_153118, NM_001114665, BC034510,
Species
mouse
UniGene ID
Mm.470230

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.