mouse FNBP1 Over-expression AAV

Name 
AAV-m-FNBP1
Cat No 
AAV-259520
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Fnbp1.

AAV-259520
AAV-m-FNBP1

Ready-to-use AAV expressing Mouse Fnbp1 (formin binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1110057E06Rik; 2210010H06Rik; FBP1; Fbp17
Description (Vector)
FNBP1 may act as a link between RND2 signaling and regulation of the actin cytoskeleton (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during the late stage of clathrin-mediated endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also enhances actin polymerization via the recruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. May be required for the lysosomal retention of FASLG/FASL.
Gene ID
14269
Gene Name (Vector)
formin binding protein 1
Gene Symbol
Fnbp1
ORF Size (aa)
1017
ORF Size (bp)
1017 bp
RefSeq ID
NM_019406
RefSeq Synonyms
NM_019406, NM_001177650, NM_001177649, NM_001177648, NM_001038700, BC003867,
Species
mouse
UniGene ID
Mm.440993

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.