mouse FAM20B Over-expression AAV

Name 
AAV-m-FAM20B
Cat No 
AAV-259046
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Fam20b.

AAV-259046
AAV-m-FAM20B

Ready-to-use AAV expressing Mouse Fam20b (family with sequence similarity 20, member B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C530043G21Rik; mKIAA0475
Description (Vector)
Responsible for the 2-O-phosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature GAG chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-o-phosphorylation may influence the catalytic activity of B3GAT3 (GlcAT-I) which completes the precursor tetrasaccharide of GAG-protein linkage regions on which the repeating disaccharide region is synthesized.
Gene ID
215015
Gene Name (Vector)
family with sequence similarity 20, member B
Gene Symbol
Fam20b
ORF Size (aa)
1230
ORF Size (bp)
1230 bp
RefSeq ID
NM_145413
RefSeq Synonyms
NM_145413, BC031473, BC024412, BC023737, BC019381,
Species
mouse
UniGene ID
Mm.229107

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.