mouse EZH1 Over-expression AAV

Name 
AAV-m-EZH1
Cat No 
AAV-258821
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ezh1.

AAV-258821
AAV-m-EZH1

Ready-to-use AAV expressing Mouse Ezh1 (enhancer of zeste 1 polycomb repressive complex 2 subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ENX-2
Description (Vector)
Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH1-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Gene ID
14055
Gene Name (Vector)
enhancer of zeste 1 polycomb repressive complex 2 subunit
Gene Symbol
Ezh1
ORF Size (aa)
2253
ORF Size (bp)
2253 bp
RefSeq ID
NM_007970
RefSeq Synonyms
NM_007970, BC007135,
Species
mouse
UniGene ID
Mm.5027

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.