mouse CPEB1 Over-expression AAV

Name 
AAV-m-CPEB1
Cat No 
AAV-256015
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Cpeb1.

AAV-256015
AAV-m-CPEB1

Ready-to-use AAV expressing Mouse Cpeb1 (cytoplasmic polyadenylation element binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AU024112; Cpeb; mCPEB
Description (Vector)
Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress.
Gene ID
12877
Gene Name (Vector)
cytoplasmic polyadenylation element binding protein 1
Gene Symbol
Cpeb1
ORF Size (aa)
1689
ORF Size (bp)
1689 bp
RefSeq ID
NM_007755
RefSeq Synonyms
NM_007755, NM_001252526, NM_001252525, BC125476,
Species
mouse
UniGene ID
Mm.273122

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.