mouse CFB Over-expression AAV

Name 
AAV-m-CFB
Cat No 
AAV-255325
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Cfb.

AAV-255325
AAV-m-CFB

Ready-to-use AAV expressing Mouse Cfb (complement factor B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI195813; AI255840; B; Bf; C2; Fb; H2-Bf
Description (Vector)
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Gene ID
14962
Gene Name (Vector)
complement factor B
Gene Symbol
Cfb
ORF Size (aa)
2286
ORF Size (bp)
2286 bp
RefSeq ID
NM_008198
RefSeq Synonyms
NM_008198, NM_001142706, BC005451,
Species
mouse
UniGene ID
Mm.653

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.