mouse CCNC Over-expression AAV

Name 
AAV-m-CCNC
Cat No 
AAV-254858
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ccnc.

AAV-254858
AAV-m-CCNC

Ready-to-use AAV expressing Mouse Ccnc (cyclin C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI451004; AU020987; CG1C
Description (Vector)
Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
Gene ID
51813
Gene Name (Vector)
cyclin C
Gene Symbol
Ccnc
ORF Size (aa)
579
ORF Size (bp)
579 bp
RefSeq ID
NM_016746
RefSeq Synonyms
NM_016746, NM_001290422, NM_001290420, NM_001122982, BC120677, BC120649, BC029211, BC003344,
Species
mouse
UniGene ID
Mm.278584

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.